the webinar: Longitudinal Monitoring
Using ChimerMarker Software
Short Tandem Repeat (STRs) provide
a highly sensitive measure of chimerism
in post-BMT monitoring which is essential
term tracking of engraftment and
early detection of magnant cell replapse.
ChimerMarker® software was developed
in collaboration with Dr.
Don Kristt, providing accurate
and long term monitoring. ChimerMarker
software is compatible with data from
all major capillary electrophoresis
human identity STR kits (including
PowerPlex®ESI) and custom chemistries.
The program has user-friendly
linked navigation; no need for error
proned data transfer. The longitudinal
graphs are easily appended with results
from sequential samples. The report
header provides verification of the
user and the analysis parameters.
The longitudinal graph is automatically
saved and easily appended with the
sequential samples during the monitoring
time period. The header provides electronic
verification of institution, user
and analysis parameters.
The Percentage Chimerism (donor or
recipient) is displayed in the Y-axis.
Sample date is displayed in the X-axis.
This Double donor monitoring report
displays the trend of engraftment
with an increase in overall chimerism
and Donor 1 stability and a decrease
in Donor 2 chimerism percentage. In
this example the analyst entered Tx
to indicate sample at transplant and
then the weeks post-transplant for
the sequential samples.
Patient information, addition of
sequential samples and comments, printing
and saving are easily accomplished
using the tool bar icons. The graph
selection includes bar format (shown
here) or line graph format. Quality
control metrics are included in the
graph and result tables.
Our Introductory and Double Donor
Chimerism Analysis Webinars
of their respective owners
Research use only (RUO)