SoftGenetics - Software PowerTools for Genetic Analysis


Macromolecule Analysis Tool: Aligns Fragments of Multiple Capillaries Without Internal Size Standards

The Macromolecule Tool aids with analysis of macromolecules without an internal lane size standard. Depending on the macromolecule size and configuration, migration rates through capillaries vary greatly, as with polysaccharides or carbohydrates. Internal size standards of the same macromolecule may not be readily available. GeneMarker® software is compatible with data from ABI®PRISM, Beckman-Coulter®, MegaBACE® capillary electrophoresis systems. This tool enables researchers to physically identify reference peaks known to have the same size and uses this information to align from one capillary to another. A user friendly Run Wizard provides rapid analysis of aligned capillaries. Characteristics of the aligned macromolecule fragments (such as relative size, peak height, peak area) can then be exported in an excel sheet or printed as final report for studies including determination of characteristics such as number and relative size of degradation products or other macromolecules, such as DNA binding carbohydrates commonly functioning in gene regulation.




Use GeneMarker software's synthetic gel image to draw a box around two size ranges (left), click apply and align the capillaries. Use the run wizard to provide aligned electropherograms, relative size of peaks, peak height and peak area.



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SoftGenetics - Software PowerTools for Genetic Analysis












SoftGenetics - Software PowerTools for Genetic Analysis





SoftGenetics - Software PowerTools for Genetic Analysis

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