SoftGenetics - Software PowerTools for Genetic Analysis

 

 

 

 

 

Expression Analysis

miRNA, ChIP-Seq, & DGE analysis

 

NextGENe software includes unique tools for analyzing small RNA, (microRNA), ChIP-Seq as well as DGE analysis of data from Illumina® iSeq, Miniseq, MiSeq, NextSeq, HiSeq, and NovaSeq systems, Ion Torrent Ion GeneStudio S5, PGM, and Proton systems as well as other platforms. The NextGENe Viewer provides biologists with the ability to review results in detail. This high level of visualization is not available in programs such as CLC Genomics Workbench, Lasergene's SeqMan Pro, as well as academic software such as MAQ & SOAP, Top Hat, BWA & Bowtie. Peak detection settings can also be manually adjusted by the user using the Peak Identification Tool in the viewer.


MicroRNA sequencing data can be aligned to the miRBase reference to detect the presence of known miRNAs, with expression levels for each miRNA sequence reported. Alternatively any small RNA sample dataset can be mapped against a genomic reference to detect novel small RNAs using the NextGENe Peak Identification Tool.


NextGENe software also includes software tools specially designed to handle chromatin immunoprecipitation DNA sequencing data (ChIP-Seq). These tools work by aligning sample data to the reference sequence, utilizing coverage for peak detection and providing a specialized peak report which includes detailed information about each peak.


When alignment and initial peak detection is completed, the results are shown in the NextGENe Viewer with peaks highlighted. The NextGENe Viewer provides biologists with the ability to review results in detail.

For More Information Review or Download Application notes:
Digital Gene Expression Application Note
ChIP-Seq_Analysis with NextGENe software
Whole Genome Alignment with NextGENe software
Small RNA Application Note
Using NextGENe software's Pipeline Automation Tool

Pricing & Trial Version:
Request 30-day trial/Price Quote

 

Reference Material:
Download/View NextGENe® Brochure
NextGENe User Manual
Annotated Reference Genomes

 

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SoftGenetics - Software PowerTools for Genetic Analysis

 

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SoftGenetics - Software PowerTools for Genetic Analysis

100 Oakwood Avenue | Suite 350 | State College, PA 16803 | USA
Phone: 814-237-9340 or 888-791-1270
Email: info@softgenetics.com

 

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