SoftGenetics - Software PowerTools for Genetic Analysis






Human Identity (Forensic) Analysis

There is tremendous potential for the use of 2nd generation sequencing, such as the Roche FLX/Junior, Ion PGM platforms or Illumina HiSeq/MiSeq systems in human identity and forensic profiling. It promises to make analysis faster and cheaper because capillary electrophoresis is eliminated and because samples can be barcoded with multiplex identifier (MID) tags and then combined to be analyzed at the same time. Additionally use of this sequencing technology increases the amount of information available such as mitochondria, which is particularly useful in profiling of degraded DNA. Comparing sequence data rather than electrophoresis results allows for the comparison of Single Nucleotide Polymorphisms (SNPs) between samples.


NextGENe is an incredibly powerful tool for working with next generation sequencing for paternity identification, criminal forensic profiling and missing person identification. It is able to accurately align thousands of reads in seconds. The built-in barcode sorting tool makes it easy to work with multiplexed samples and the NextGENe pipeline tool, AutoRun allows for continual, unattended profiling. SNPs are conveniently displayed in the mutation report while STR polymorphisms are counted and the results are displayed in the expression report.


Review FSIG 2013 poster from NIST


For FSI: Genetics mtDNA article click here


For more information Review or Download Application notes:
Human Identity Analysis with NextGENe software
Reducing error of NGS Sequencing data with NextGENe Condensation™ Tool
NextGENe Illumina SNP_Indel_Detection
NextGENe software Variant Comparison Tool
Mutation Confidence Scoring with NextGENe software
NextGENe SNP & Indel Viewer
Paired end read merging with NextGENe software
Sequence Analysis Using Barcode/Index Tags of Pooled Samples with NextGENe Software
Using NextGENe software's Pipeline Automation Tool
Plugin for Torrent Browser automation
Demultiplexing Illumina® MiSeq™ Data
Working with Circular Reference Sequences in NextGENe® Software


Pricing & Trial Version:
Request 30-day trial/Price Quote


Reference Material:
Download/View NextGENe® Brochure
NextGENe User Manual
Annotated Reference Genomes

SoftGenetics - Software PowerTools for Genetic Analysis


SoftGenetics - Software PowerTools for Genetic Analysis




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