SoftGenetics - Software PowerTools for Genetic Analysis

 

 

 

 

ThunderBolts™ Panel Analysis

A major challenge facing today's cancer researchers is the ability to have highly accurate, simple, and low-cost tools to rapidly identify genetic variants underlying specific phenotypes found in solid tumors and hematological cancers. The combination of the RainDance ThunderBolts™ System, the ThunderBolts NGS gene panels, and SoftGenetics NextGENe® Software enables targeted sequencing for research of important oncogenes that have clinical relevance to cancer diseases. The solution features preloaded analysis templates for each gene panel and pre-defined settings for detecting minor allele frequencies at different sensitivity settings (1% and 5%).

 

NextGENe version 2.4.1 introduces AutoRun Templates for quick project setup using various types of library preparations. The ThunderBolts Cancer Panels and ThunderBolts Myeloid Panels are installed by default. They can be loaded into the NextGENe AutoRun tool to quickly set up a job to process multiple samples. For each panel, NextGENe includes a template with 5% allele frequency cutoff and a "High Sensitivity" template with 1% allele frequency cutoff. These pre-defined templates cannot be modified, but they may be used to create new custom templates by users with adequate permissions. These templates help to ensure that technicians are using the appropriate settings and automatically creating the necessary reports. After processing, researchers can view projects in the NextGENe Viewer and (optionally) export to Geneticist Assistant™.

 

Panel templates offer an easier approach for targeted resequencing data in NextGENe. Templates are used to specify all settings for the analysis when creating ngjob files. These ngjob files are detected and processed by the AutoRun tool, when sequencing data is available.

 


The NextGENe AutoRun Tool’s Job File Editor includes built-in templates for ThunderBolts panels.

 


NextGENe Viewer display with Mutation Report listing detected variants

 


The Coverage Curve Target Region Statistics reports coverage information such as % of reads on target, minimum, maximum and average coverage across all targets, and the percentage of targets covered at a user-set coverage level.

 

For further information please review or download the following Application Note:
NextGENe® Software Analysis of Solid Tumors and Hematological Cancers Using RainDance ThunderBolts™ NGS Panels

 

Webinar:
Analysis of Raindance Thunderbolts Panel Data with NextGENe Software (View) (view on )

 

Pricing & Trial Version:
Request 30-day trial/Price Quote

 

Reference Material:
Download/View NextGENe® Brochure
NextGENe User Manual
Annotated Reference Genomes

 

SoftGenetics - Software PowerTools for Genetic Analysis

 

SoftGenetics - Software PowerTools for Genetic Analysis

 

 

SOFTWARE


Review all of our software products

 

 

 

 

 

 

 

 

 

SoftGenetics - Software PowerTools for Genetic Analysis

 

 

 

SoftGenetics Software PowerTools for Genetic Analysis provides current up-to-date information and pricing on all products.
All requests are secure.

 

SoftGenetics - Software PowerTools for Genetic Analysis

 

 

EXPERTISE


Request trial versions of our software and tap into our knowledge base

 

 

Trial Software

All of our software products are available for review and trial periods. Please use link to request a trial version.

 

Request Trial >>

 

Online Training

Our software professionals are available to you for online training of any of our products. Please contact an expert now.

 

Request Training >>

 

Webinars

SoftGenetics provides online webinars to assist you in the growing knowledge of our products. Visit our Analysis Corner.

 

View Webinars >>

 

SoftGenetics - Software PowerTools for Genetic Analysis

 

 

SEND US A MESSAGE


Representatives are always ready to assist you


Name *
Email *
Phone

###
-
###
-
####
Message *

 

SoftGenetics - Software PowerTools for Genetic Analysis

100 Oakwood Avenue | Suite 350 | State College, PA 16803 | USA
Phone: 814-237-9340 or 888-791-1270
Email: info@softgenetics.com

 

© 2020 SoftGenetics, LLC. All rights reserved

Trademarks are property of their respective owners

Research use only (RUO)

 

Web design by Lovett Creations