SoftGenetics - Software PowerTools for Genetic Analysis

 

 

 

 

 

Copy Number Variation (CNV) Analysis

NextGENe software provides three options for CNV for the various needs of molecular genetics laboratories:

  1. The NextGENe CNV tool. Validated for Clinical applications is used to compare a single sample with either a single control or group of controls. The CNV tool can be used for targeted panels and Whole Exome Sequencing (WES). Since it relies on normalized coverage values, adequate base coverage is important. Both the sample and control (control group) should be run with the same chemistry and similar run conditions.
  2. NextGENe software’s Batch CNV tool can be used to compare several samples to one another, but without controls. It has been shown to be concordant with a Sanger/MLPA® combo approach. When used as a screening function, the Batch CNV Tool has been shown to significantly reduce costs, while greatly enhancing analysis efficiency in laboratories performing MLPA.

    The method is ideal for CNV panels such as NimbleGen Seq Cap targeted panels and other chemistries with low noise, (minimal effect on sensitivity/specificity – WES may be too noisy). The tool can simultaneously analyze up to 228 total data points, for example 24 samples with each targeting 11 Mbps.
  3. NextGENe software’s Sensitive Aneuploidy Detection (SAD) tool is designed for chromosome copy number detection in Whole Genome Sequencing (WGS) for cell-free DNA (cfDNA) applications, such as non-invasive prenatal testing (NIPT). The tool is streamlined for simple operation and the normalization process allows for detection of aneuploidies, even those with a high background of non-aneuploid data. Due to the level of normalization required, this tool uses a modeling control group of at least 30 samples generated by the same chemistry.

Pricing & Trial Version:
Request 30-day trial/Price Quote

 

Reference Material:
Download/View NextGENe® Brochure
NextGENe User Manual
Annotated Reference Genomes

 

Trademarks property of their respective owners

SoftGenetics - Software PowerTools for Genetic Analysis

 

SoftGenetics - Software PowerTools for Genetic Analysis

 

 

SOFTWARE


Review all of our software products

 

 

 

 

 

 

 

 

 

SoftGenetics - Software PowerTools for Genetic Analysis

 

 

 

SoftGenetics Software PowerTools for Genetic Analysis provides current up-to-date information and pricing on all products.
All requests are secure.

 

SoftGenetics - Software PowerTools for Genetic Analysis

 

 

EXPERTISE


Request trial versions of our software and tap into our knowledge base

 

 

Trial Software

All of our software products are available for review and trial periods. Please use link to request a trial version.

 

Request Trial >>

 

Online Training

Our software professionals are available to you for online training of any of our products. Please contact an expert now.

 

Request Training >>

 

Webinars

SoftGenetics provides online webinars to assist you in the growing knowledge of our products. Visit our Analysis Corner.

 

View Webinars >>

 

SoftGenetics - Software PowerTools for Genetic Analysis

 

 

SEND US A MESSAGE


Representatives are always ready to assist you


Name *
Email *
Phone

###
-
###
-
####
Message *

 

SoftGenetics - Software PowerTools for Genetic Analysis

100 Oakwood Avenue | Suite 350 | State College, PA 16803 | USA
Phone: 814-237-9340 or 888-791-1270
Email: info@softgenetics.com

 

© 2020 SoftGenetics, LLC. All rights reserved

Trademarks are property of their respective owners

Research use only (RUO)

 

Web design by Lovett Creations