USER
MANAGEMENT AND VALIDATION TOOLS
ChimerMarker® software is a biologist-friendly
genotyping program with additional
tools to assist researchers with DNA
fragment analysis. The program is
compatible with all capillary electrophoresis
instruments (ABI®PRISM, Beckman-Coulter®,
MegaBACE®) and is a powerful alternative
to GeneMapper®, Genotyper™,
GeneScan®, CEQ™ Fragment
Analysis Software. In addition to
accurate
size calling algorithm options
and a flexible panel
editor, ChimerMarker software includes
User
Management and Project
Comparison Tools. User management
provides control of user access rights,
automatically generates an audit
trail of all edits to genotyping
projects and is used to customize
the Organization and Operator fields
in the header of comprehensive chimerism
reports. The Project ComparisonTool
provides researchers with a linked
comparison of two replicate projects.
It is an excellent validation tool
for instrumentation, analysis parameters
or chemistries; providing a peak by
peak comparison and identifying any
differences between the project results.
Uses include establishing and comparing
analysis parameters, validation studies
for instrumentation or chemistries,
and ensuring consistent calls of edited
alleles (especially beneficial for
long term projects to confirm that
edits/comments are consistently applied).
COMPLETE
AUDIT TRAIL
Figure 1: User management
provides a complete audit trail of
any edit made by the authorized user;
including the time, organization,
user ID, operation performed and current
and original values.
CUSTOMIZED
HEADER OF FINAL REPORT - ELECTRONIC
VERIFICATION
Figure 2: This enlarged
header displays information from user
management (Lab name and Identification
of the individual that performed the
analysis. Access rights are selected
for each user and provide assurance
that authorized individuals have access
to the appropriate functions in the
software.
PROJECT
COMPARISON TOOL REDUCES FATIGUE AND
SAVES TIME
Figure 3:
The peak-by-peak comparison is summarized
in the table at the right. Results
that are in agreement with each other
are not highlighted (as seen here
with samples 6 and 7 in the table).
Any differences between the samples
will be highlighted in the tables
and electropherograms. By using the
scroll bar to scan for yellow highlighting,
the reviewer or supervisor can quickly
zoom in on the areas of interest by
double clicking on the yellow cells.
Review
Our Introductory and Double Donor
Chimerism Analysis Webinars
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