To add a variant interpretation
1. Open the Variant sub-tab on the Patient tab or the Sample Variant Data sub-tab on the Sample tab.
2. Select a single variant, or CTRL-click to select multiple variants and then right-click to open the sub-tab context menu.
3. On the context menu, select Edit Variant and then if:
• A single variant is selected, select Add Single Variant Interpretation to open the Add Single Variant Interpretation dialog box.
• Two or more variants are selected, select Add Compound Variant Interpretation to open the Add Compound Variant Interpretation dialog box. All the selected variants are displayed in the Included Variants (left) pane when the dialog box opens.
4. Do one of the following:
• For a single variant, in the blank Interpretation pane, enter the appropriate comment or description, and then click OK.
The Add Single Variant Interpretation dialog box closes. The interpretation is displayed in the Interpretation column on the Variants sub-tab for the Patient tab.
• For two or more variants, in the Interpretation Name field:
i Enter an identifying name for the interpretation.
ii. Leave all the variants as-is in the Included Variants pane, or optionally, select one or more included variants (CTRL-click to select multiple variants), and then click the Move arrow to move these selected variants to the Excluded Variants (right) pane.
iii. Optionally, in the Interpretation field, enter a description of the interpretation.
iv. Click OK.
The Add Compound Variant Interpretation dialog box closes. If you open the Sample tab from the Patient tab, then you can see the interpretation displayed in the Compound Variant Interpretations pane on the Sample Data sub-tab. You can double-click an interpretation that is displayed in the Compound Variant Interpretations pane to open a Compound Variant Interpretation sub-tab that displays the variants that are included for the interpretation. See
Compound Variant Interpretation Sub-Tab.