Functional Prediction tab

NextGENe Online Help : Variation Track Settings : dbNSFP Track Settings : Functional Prediction tab

Setting	Description
At least [ ] Criteria Satisfied	The default value is one. A variant must pass the filtering settings for only one of the available conservation scores to be displayed in the Mutation report. Increase this value as needed.
Filtering Settings	The score threshold, which has a default value of < 0. You can modify this value for each available functional prediction method. Optionally, you can also specify classifications for the variant, for example, D-Probably Damaging, P-Possibly Damaging, B-Benign, and/or No Data. Note: If you specify classifications for a variant, then the variant must meet both the score threshold and the classification requirements to be displayed in the Mutation report.

Setting

Description

At least [ ] Criteria Satisfied

The default value is one. A variant must pass the filtering settings for only one of the available conservation scores to be displayed in the Mutation report. Increase this value as needed.

Filtering Settings

The score threshold, which has a default value of < 0. You can modify this value for each available functional prediction method. Optionally, you can also specify classifications for the variant, for example, D-Probably Damaging, P-Possibly Damaging, B-Benign, and/or No Data.

Note: If you specify classifications for a variant, then the variant must meet both the score threshold and the classification requirements to be displayed in the Mutation report.