At times, critical information such as chromosome information and gene name are not contained in the first line of an mRNA GenBank file. Instead, this information is found deeper in the file, in the file body. Because the NextGENe software uses the first line of an mRNA file as the title for the GenBank reference file, you use the Modify Titles for mRNA GenBank tool to include this critical information and therefore, ensure that this information is retained. The figure below illustrates this.