The Variant Comparison tool
You use the Variant Comparison tool to compare the variant calls in two or more aligned projects that use the same reference sequence. Typically, you use to the tool to compare up to 20 multiple projects to show variant calls that meet specific criteria, such as variant calls that are shared among all the projects and that meet a minimum coverage requirement. For certain data sets, however, additional functionality is available.
If tumor/normal comparison data is available, you can use the Top List function to analyze somatic variants.
If family data (relationship and phenotype) is available, you can use specific family data comparison options to help you to narrow the list of possible causative variants.
See: