Error Correction
The Error Correction method is very similar to the Consolidation and Elongation methods. Reads are clustered in the same fashion and low frequency errors are corrected; however, read length is not extended and reads are not merged. Instead, each original read is maintained at its original length with the instrument errors corrected.
The figure below is an example of SNP discovery using the Condensation Tool. On the left side of this figure, raw reads are aligned to the reference. Low frequency variations, most likely errors, are highlighted in gray while variant calls are highlighted in blue. On the right of the figure, condensed reads are aligned to the reference. The likely errors were eliminated while the true SNP was maintained.
SNP discovery with the Condensation Tool