GeneMarker®HTS Forensic NGS Analysis Software

GeneMarker®HTS software provides a validated streamlined workflow for forensic mitochondrial , STR, and Y-STR casework as well as medical research of mitochondrial DNA from massively parallel squencing platforms (MPS) - such as the Illumina® and Ion Torrent® - in an easy-to-use Windows® operating system.

GeneMarkerHTS (High Through-put Sequence) Forensic Analysis Software for data from Next Generation Sequence (NGS), Massively Parallel Sequencing (MPS) platforms, including Illumina® and Ion Torrent®

Mitochondrial DNA Analysis

• Whole Genome, HVI/HVII and control region analysis
• Unique Alignment Technology ∙ Motif Consensus
• Forensic Nomenclature
• Easy Upload to EMPOP

STR Analysis

• Autosomal & Y-STR
• Forensic Nomenclature
• Genotype & SNP Reporting
• Concordant

Validated Easy-to-Use Windows® Interface

Compatible with major Chemistries & Platforms

Audit Trail & User Control

Comprehensive Reporting Options

GeneMarkerHTS software includes:

• Audit trail capability
• User management
• Customizable viewing and reporting to protect privacy of personal health information (PHI)
• Profile Comparison Capabilities
• Upload to EMPOP
• Rapid Analysis – get results in minutes
• mtDNA:
  • 30 MiSeq whole mtDNA chromosome data files with 10,000 average depth of coverage were aligned in 90 minutes (3 minutes per sample).
  • 200 whole mtDNA chromosome data files with 10,000 average depth of coverage aligned in 16 hours.
• STR/Y-STR
  • GeneMarker HTS software results were 99.74% concordant with the CE allele calls of 20,000 sampled GeneMarker loci.
  • Samples allele calls and iso-alleles

---

Webinars:

• Introduction to mtDNA Analysis in GeneMarkerHTS
• STR Analysis in GeneMarkerHTS

Reference Materials:

• Validation of NGS for mitochondrial DNA casework at the FBI Laboratory
• The time is now for ubiquitous forensic mtMPS analysis

Trademarks property of their respective owners
Research Use Only