Mutation Surveyor® DNA Variant Analysis Software

Mutation Surveyor software includes patented anti-correlation technology, which physically compares sample sequence traces to a reference trace, providing accuracy up to 99.5% with Phred 20 bi-directional sequences and a sensitivity of 5% of the primary peak.

A Unique tool for DNA Variant Analysis from Sanger Sequencing Traces

Mutation Surveyor® software is a powerful and accurate DNA Sequencing analysis tool for Sanger Sequencing files generated by the following electrophoresis systems:

  • Applied Biosystems Genetic Analyzers
  • Beckman CEQ
  • Promega Spectrum Compact CE System

Download the Mutation Surveyor Brochure, or request a free, 30-day trial today, and see how our PowerTools can greatly assist you with your genetic analyses.

Capable of performing variant analysis of up to 2000 Sanger sequencing files (.ab1, .RSD, .ESD & .scf) in 15 minutes, Mutation Surveyor delivers excellent accuracy, sensitivity, and low false-positive and false-negative rates in the analysis of DNA variants, including:

The Mutation Surveyor package includes patented anti-correlation technology (U.S. Patent 8,086,410), which physically compares sample sequence traces to a reference trace, providing accuracy up to 99.5% with Phred 20 bi-directional sequences and a sensitivity of 5% of the primary peak.

Along with increased accuracy and sensitivity, Mutation Surveyor software features many tools:

Mutation Surveyor software includes features designed to enhance and optimize the process of variant discovery in Sanger sequencing traces. The software can automatically align traces to GRCh37 or GRCh38 GenBank references. And the variant knowledge database allows users to track variants by chromosomal position, indicate false positives and other artifacts, and query mutation annotation information from popular variant databases such as dbSNP, dbNSFP, ClinVar, and gnomAD.

Also included in Mutation Surveyor software is an intuitive user management system, which enables administrators to set up password-protected user names, control access rights, and generate a user audit trail. Access rights for each user are determined by the administrator, providing assurance that unauthorized individuals do not accidentally alter a project or change the analysis parameters established by the laboratory. User management also provides the user ID in the header of the final reports.


Application Notes:

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